Endovascular thrombectomy interventions leads to higher favourable functional outcome at the end of compared with standard therapy (high certainty).
Endovascular thrombectomy interventions leads to lower death from all causes at the end of compared with standard therapy (high certainty).
Endovascular thrombectomy interventions showed no clear difference in symptomatic intracranial haemorrhage at the end of compared with standard therapy (high certainty).
Endovascular thrombectomy interventions probably leads to higher neurological status at the end of compared with standard therapy (moderate certainty).
Endovascular thrombectomy interventions probably leads to higher degree of recanalisation (TIMI grade) compared with standard therapy (moderate certainty).
Thrombo‐aspiration alone showed no clear difference in functional independence at 3 months (mRS 0 to 2) (primary outcome) compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in successful reperfusion (mTICI 2b to 3) postprocedure compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in all‐cause mortality within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in intracranial hemorrhage on imaging at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in symptomatic intracranial hemorrhage at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in procedure‐related adverse events within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).