Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

173 questions · 174 findings · 12 reviews · Headline outcomes only

No studies found 34 · 19.5%GRADE not reported 26 · 14.9%Very low 34 · 19.5%Low 40 · 23%Moderate 25 · 14.4%High 15 · 8.6%

Doxycycline vs quinolones

Microbiological failure Men and women Doxycycline 100 mg twice a day for 7 days vs ofloxacin 300 mg once a day for 7 days · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…
1 finding from 1 review

Doxycycline vs quinolones

Clinical failure Men Doxycycline 100 mg twice a day for 7 days vs ofloxacin 400 mg once a day for 7 days · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether doxycycline changes clinical failure Men Doxycycline 100 mg twice a day for 7 days vs… compared with quinolones (very low certainty).

1 finding from 1 review

Doxycycline vs quinolones

Clinical failure Women Doxycycline 100 mg twice a day for 7 days vs ofloxacin 400 mg once a day for 7 days. · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether doxycycline changes clinical failure Women Doxycycline 100 mg twice a day for 7 days vs… compared with quinolones (very low certainty).

1 finding from 1 review

Doxycycline vs quinolones

Microbiological failure Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether doxycycline changes microbiological failure Men Doxycycline 100 mg twice a day for 7… compared with quinolones (very low certainty).

1 finding from 1 review

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in physician‐assessed improvement in rosacea severity Investigator's… compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in participant‐assessed improvement in rosacea severity Excellent… compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review