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Evidence found and GRADE certainty

11 questions · 12 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 6 · 50%Moderate 6 · 50%High 0 · 0%

Dopamine agonist vs placebo

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).

1 finding from 1 review

Dopamine agonist vs placebo

Point abstinence (number of participants who were abstinent at the end of the treatment) · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in abstinence (objective) Participants abstinent at the end of… compared with placebo (low certainty).

1 finding from 1 review

Amantidine vs antidepressants

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Amantidine showed no clear difference in adverse events as N of participants with at least one adverse event compared with antidepressants (low certainty).

1 finding from 1 review

Amantadine vs placebo

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).

1 finding from 1 review

Amantadine vs placebo

Abstinence · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in abstinence (objective) N of subjects abstinent at the end of the study compared with placebo (low certainty).

2 findings from 1 review