Findings

What do systematic reviews say?

15 questions · 15 findings · 1 reviews · Kidney and Transplant

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No studies found 3 · 20%GRADE not reported 3 · 20%Very low 2 · 13.3%Low 7 · 46.7%Moderate 0 · 0%High 0 · 0%

Dihydropyridine vs non‐dihydropyridine calcium channel blockers

Predialysis systolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Dihydropyridine vs non‐dihydropyridine calcium channel blockers

Diastolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Dihydropyridine vs non‐dihydropyridine calcium channel blockers

Cardiovascular mortality · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
GRADE not reported

Dihydropyridine vs non‐dihydropyridine calcium channel blockers

Intradialytic hypotension · people with CKD requiring dialysis

The review found no eligible studies for this question.

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dihydropyridine vs non‐dihydropyridine calcium channel blockers

Other side effects1,5 · people with CKD requiring dialysis

It is very uncertain whether dihydropyridine changes other side effects1,5 compared with non‐dihydropyridine calcium channel blockers (very low certainty).

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
RR 0.13 [0.01, 2.36]
1 study · 40 participants
Very low

Dihydropyridine calcium channel blockers vs placebo or control

Predialysis systolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Dihydropyridine calcium channel blockers vs other antihypertensives

Other side effects · people with CKD requiring dialysis

The review found no eligible studies for this question.

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dihydropyridine calcium channel blockers vs placebo or control

Diastolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Low

Dihydropyridine calcium channel blockers vs placebo or control

Cardiovascular mortality · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 124 participants
GRADE not reported

Dihydropyridine calcium channel blockers vs placebo or control

Intradialytic hypotension · people with CKD requiring dialysis

Dihydropyridine calcium channel blockers showed no clear difference in intradialytic hypotension compared with placebo/control (low certainty).

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
RR 0.54 [0.25, 1.15]
2 studies · 287 participants
Low

Dihydropyridine calcium channel blockers vs placebo or control

Other side effects · people with CKD requiring dialysis

The review found no eligible studies for this question.

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dihydropyridine calcium channel blockers vs other antihypertensives

Predialysis systolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 180 participants
Low

Dihydropyridine calcium channel blockers vs other antihypertensives

Diastolic blood pressure · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 180 participants
Low

Dihydropyridine calcium channel blockers vs other antihypertensives

Cardiovascular mortality · people with CKD requiring dialysis

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 164 participants
GRADE not reported

Dihydropyridine calcium channel blockers vs other antihypertensives

Intradialytic hypotension · people with CKD requiring dialysis

It is very uncertain whether dihydropyridine calcium channel blockers changes intradialytic hypotension compared with other antihypertensives (very low certainty).

1 finding from 1 review

Calcium channel blockers for people with chronic kidney disease requiring dialysis 2020 · Cochrane Headline outcomes only
RR 2.88 [0.12, 68.79]
1 study · 92 participants
Very low