What do systematic reviews say?

Adults: prednisolone vs dexamethasone

It is very uncertain whether adults: prednisolone changes new exacerbation during compared with dexamethasone (very low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 1.32 [0.39, 4.47]
  1 study · 200 participants
  Very low
• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 1.85 [0.43, 7.96]
  1 study · 200 participants
  Very low

Children: prednisolone vs dexamethasone

Children: prednisolone showed no clear difference in admission at initial presentation compared with dexamethasone (low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 1.08 [0.74, 1.58]
  3 studies · 1007 participants
  Low

Children: prednisolone vs dexamethasone

Children: prednisolone showed no clear difference in re‐admission during compared with dexamethasone (low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 0.44 [0.15, 1.33]
  3 studies · 985 participants
  Low

Children: prednisolone vs dexamethasone

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 328 participants
  Very low
• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 533 participants
  GRADE not reported

Children: prednisolone vs dexamethasone

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 255 participants
  GRADE not reported

Children: prednisolone vs dexamethasone

Children: prednisolone showed no clear difference in new exacerbation during compared with dexamethasone (low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 0.85 [0.54, 1.34]
  4 studies · 981 participants
  Low

Adults: prednisolone vs dexamethasone

It is very uncertain whether adults: prednisolone changes re‐admission during compared with dexamethasone (very low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 0.35 [0.04, 3.47]
  1 study · 200 participants
  Very low

Adults: prednisolone vs dexamethasone

Adults: prednisolone showed no clear difference in asthma symptoms Returned to normal activities within 3 days compared with dexamethasone (low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 0.44 [0.19, 1.01]
  1 study · 191 participants
  Low