Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 2 reviews · Injuries

No studies found 7 · 28%GRADE not reported 0 · 0%Very low 7 · 28%Low 10 · 40%Moderate 1 · 4%High 0 · 0%

DDAVP vs tranexamic acid (control)

All thrombotic events (including myocardial infarction, ischaemic stroke, other arterial thromboembolism, and venous thromboembolism) · participants undergoing surgery

It is very uncertain whether DDAVP changes all thrombotic events (including myocardial infarction, ischaemic… compared with tranexamic acid (very low certainty).

1 finding from 1 review

DDAVP vs placebo or usual care

Number of participants receiving a red cell transfusion (total) · participants undergoing surgery

DDAVP showed no clear difference in number of participants receiving a red cell transfusion (total) compared with placebo or standard care (moderate certainty).

1 finding from 1 review

DDAVP vs aprotinin

Number of participants receiving a red cell transfusion (total) · participants undergoing surgery

DDAVP may leads to higher number of participants receiving a red cell transfusion (total) compared with aprotinin (low certainty).

1 finding from 1 review