Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 11 findings · 2 reviews · Incontinence

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 45.5%Low 4 · 36.4%Moderate 2 · 18.2%High 0 · 0%

Alarm plus other intervention vs other interventions

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm plus other intervention may leads to higher proportion of children achieving 14 consecutive dry nights by the… compared with other intervention (low certainty).

1 finding from 1 review

Tricyclic antidepressants vs Other Drug for

Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis

It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights at the end of… compared with another drug (very low certainty).

2 findings from 1 review

Intervention not reported

Number of wet nights per week at the end of treatment ‐ Amitriptyline + desmopressin vs amitriptyline · children with nocturnal enuresis
1 finding from 1 review

Alarm vs desmopressin

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm showed no clear difference in proportion of children achieving 14 consecutive dry nights by the… compared with desmopressin (low certainty).

1 finding from 1 review

Alarm vs desmopressin

Proportion of children with adverse events · children with nocturnal enuresis

Alarm probably leads to lower proportion of children with adverse events compared with desmopressin (moderate certainty).

1 finding from 1 review