Findings

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Evidence found and GRADE certainty

36 questions · 36 findings · 1 reviews · Epilepsy

No studies found 0 · 0%GRADE not reported 1 · 2.8%Very low 8 · 22.2%Low 12 · 33.3%Moderate 10 · 27.8%High 5 · 13.9%

Intervention not reported

Seizure freedom (3‐month blinded evaluation period) · adults with IQ > 70 with refractory focal epilepsy

The intervention showed no clear difference in seizure freedom (3‐month blinded evaluation period) (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Neuropsychological outcome (3 months) · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Quality of life · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Seizure freedom (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy

The intervention showed no clear difference in seizure freedom (1‐ to 3‐month blinded evaluation period) (moderate certainty).

1 finding from 1 review

Intervention not reported

Responder rate (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy

The intervention showed no clear difference in responder rate (1‐ to 3‐month blinded evaluation period) (low certainty).

1 finding from 1 review

Intervention not reported

Seizure frequency reduction (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Adverse events · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Neuropsychological outcome (1 to 2 months) · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Quality of life (2 months) · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review

Intervention not reported

Seizure freedom (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy

The intervention showed no clear difference in seizure freedom (1‐ to 3‐month blinded evaluation periods) (moderate certainty).

1 finding from 1 review

Intervention not reported

Responder rate (3‐month blinded evaluation period) · adults with IQ > 70 with refractory focal epilepsy

The intervention showed no clear difference in responder rate (3‐month blinded evaluation period) (moderate certainty).

1 finding from 1 review

Intervention not reported

Responder rate (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy

The intervention showed no clear difference in responder rate (1‐ to 3‐month blinded evaluation periods) (low certainty).

1 finding from 1 review

Intervention not reported

Seizure frequency (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Adverse events · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Neuropsychological outcome (1‐ to 3‐month periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Seizure freedom (3‐month blinded evaluation period) · adults with IQ >70 with refractory focal epilepsy

The intervention showed no clear difference in seizure freedom (3‐month blinded evaluation period) (low certainty).

1 finding from 1 review

Intervention not reported

Responder rate (3‐month blinded evaluation period) · adults with IQ >70 with refractory focal epilepsy

The intervention showed no clear difference in responder rate (3‐month blinded evaluation period) (low certainty).

1 finding from 1 review

Intervention not reported

Seizure frequency reduction (3‐month blinded evaluation period) · adults with IQ >70 with refractory focal epilepsy
1 finding from 1 review