What do systematic reviews say?

Closed‐system transfer device plus safe handling vs safe handling alone

It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide alone compared with safe handling alone (very low certainty).

• Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing… 2018 · Cochrane Headline outcomes only
  RR 0.83 [0.46, 1.52]
  Studies not reported
  Very low

Closed‐system transfer device plus safe handling vs safe handling alone

It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide‡ compared with safe handling alone (very low certainty).

• Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low
• Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing… 2018 · Cochrane Headline outcomes only
  RR 0.89 [0.78, 1.01]
  Studies not reported
  Very low

Closed‐system transfer device plus safe handling vs safe handling alone

It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide or ifosfamide compared with safe handling alone (very low certainty).

• Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing… 2018 · Cochrane Headline outcomes only
  RR 0.09 [0, 2.79]
  Studies not reported
  Very low

Closed‐system transfer device plus safe handling vs safe handling alone

• Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low