Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 100%High 0 · 0%

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Primary: investigator‐rated good/excellent control of symptoms · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam showed no clear difference in primary: investigator‐rated good/excellent control of symptoms compared with vehicle foam (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Primary: participant‐rated good/excellent control of symptoms · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam probably leads to higher primary: participants with self‐rated good/excellent control of… compared with vehicle foam (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Number of participants with any adverse event (primary tolerability outcome) · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam showed no clear difference in primary: adverse events ‐ at least 1 adverse event compared with vehicle foam (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Primary: adverse events ‐ any adverse event treatment‐related (application site pruritus) · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam showed no clear difference in primary: adverse events ‐ any adverse event treatment‐related… compared with vehicle foam (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Secondary: reduction in severity, participant‐rated scoring · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam probably leads to higher secondary: reduction in severity, participant‐rated scoring compared with vehicle foam (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: clobetasol propionate foam vs vehicle foam

Secondary: reduction in severity, investigator‐rated scoring ‐ improvement at least 2 grades · participants with moderate to severe hand eczema

Corticosteroid creams/ointments: clobetasol propionate foam showed no clear difference in secondary: reduction in severity, investigator‐rated scoring ‐… compared with vehicle foam (moderate certainty).

1 finding from 1 review