Findings

What do systematic reviews say?

10 questions · 10 findings · 2 reviews · Pain, Palliative and Supportive Care

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No studies found 0 · 0%GRADE not reported 1 · 10%Very low 1 · 10%Low 6 · 60%Moderate 2 · 20%High 0 · 0%

CBT‐combined vs control

Observer‐reported distress · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 765 participants
Low

CBT‐combined vs control

Behavioral measures‐ pain · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 95 participants
Very low

CBT‐combined vs control

Behavioral measures‐ distress · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1105 participants
Low

CBT‐combined vs control

Self‐reported pain · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1359 participants
Low

CBT‐combined vs control

Self‐reported distress · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 234 participants
Low

CBT‐combined vs control

Observer‐reported pain · children aged 3‐18 years with mixed medical (acute or chronic illness) or generally healthy undergoing immunization, intravenous…

1 finding from 1 review

Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 385 participants
Low

Intervention not reported

Total studies: 38 Total participants: 12,985 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…

1 finding from 1 review

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
38 participants
GRADE not reported

Intervention not reported

Mirtazapine RCTs: 1 Participants: 406 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…

1 finding from 1 review

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Low

Intervention not reported

Duloxetine RCTs: 26 Participants: 7952 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…

1 finding from 1 review

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
26 participants
Moderate

Intervention not reported

Milnacipran RCTs: 5 Participants: 3109 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…

1 finding from 1 review

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
5 participants
Moderate