What do systematic reviews say?

Clotrimazole (partially absorbed from GI tract) vs placebo

Clotrimazole (partially absorbed from GI tract) showed no clear difference in mycological: eradication of oral candidiasis compared with placebo; GRADE not reported.

• Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
  RR 6.13 [0.38, 99.14]
  1 study · 13 participants
  GRADE not reported

Clotrimazole (partially absorbed from GI tract) vs placebo

Clotrimazole (partially absorbed from GI tract) showed no clear difference in clinical: eradication of oral candidiasis compared with placebo; GRADE not reported.

• Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
  RR 3.43 [0.51, 22.94]
  1 study · 13 participants
  GRADE not reported

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Antifungal drugs partially absorbed from GI tract (miconazole,… showed no clear difference in systemic fungal infection compared with placebo or no treatment; GRADE not reported.

• Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
  RR 2.27 [0.23, 22.56]
  1 study · 32 participants
  GRADE not reported

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

• Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
  2 studies, 60 participants; effect not estimable (no events reported)
  2 studies · 60 participants
  GRADE not reported

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Antifungal drugs partially absorbed from GI tract (miconazole,… led to lower oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.

• Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
  RR 0.16 [0.06, 0.46]
  4 studies · 292 participants
  GRADE not reported

Antifungal drugs partially absorbed from GI tract (miconazole, clotrimazole) vs placebo or no treatment

Antifungal drugs partially absorbed from GI tract (miconazole,… showed no clear difference in empirical antifungal treatment compared with placebo or no treatment; GRADE not reported.

• Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
  RR 3.38 [0.15, 77.12]
  1 study · 32 participants
  GRADE not reported

Partially absorbed antifungal drug (e.g., clotrimazole, miconazole) vs Drug not absorbed from GI tract (e.g., nystatin, amphotericin B)

The review found no eligible studies for this question.

• Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
  There were no trials comparing partially absorbed drugs with either absorbed drugs or drugs not absorbed.
  0 studies
  No studies found