Cyclophosphamide alone · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide alone compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.83 [0.46, 1.52]
Studies not reported
Very low
Cytarabine · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes cytarabine compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.72 [0.18, 2.86]
Studies not reported
Very low
Gemcitabine · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes gemcitabine compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.96 [0.6, 1.54]
Studies not reported
Very low
Irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir, epirubicin, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir,… compared with safe handling alone (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Patient‐care areas · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
5‐fluorouracil, cytarabine, gemcitabine, irinotecan, docetaxel, paclitaxel, vinorelbine, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Cyclophosphamide · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide‡ compared with safe handling alone (very low certainty).
2 findings from 1 review
no estimate extracted
Studies not reported
Very low
RR 0.89 [0.78, 1.01]
Studies not reported
Very low
Epirubicin · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes epirubicin compared with safe handling alone (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
5‐fluorouracil, cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Other measures of contamination · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cyclophosphamide or ifosfamide · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes cyclophosphamide or ifosfamide compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.09 [0, 2.79]
Studies not reported
Very low
Health outcomes · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Potential cost savings · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Cyclophosphamide, ifosfamide, or gemcitabine · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Other measures of exposure · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pharmacy areas · healthcare staff who handle infusional hazardous drugs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ifosfamide · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes ifosfamide compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.94 [0.74, 1.19]
Studies not reported
Very low
Methotrexate · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes methotrexate compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.84 [0.58, 1.22]
Studies not reported
Very low