What do systematic reviews say?

Central and local monitoring only vs central and local monitoring with on‐site visits

The review found no eligible studies for this question.

• Monitoring strategies for clinical intervention studies 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Central and local monitoring only vs central and local monitoring with on‐site visits

It is very uncertain whether central and local monitoring only changes impact of the monitoring strategy on compared with central and local monitoring with on‐site visits (very low certainty).

• Monitoring strategies for clinical intervention studies 2021 · Cochrane Headline outcomes only
  OR 0.8 [0.5, 1.1]
  1 study · 4371 participants
  Very low

Central and local monitoring only vs central and local monitoring with on‐site visits

• Monitoring strategies for clinical intervention studies 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Central and local monitoring only vs central and local monitoring with on‐site visits

Central and local monitoring only probably leads to higher combined outcome of proportion of participants with major or… compared with central and local monitoring with on‐site visits (moderate certainty).

• Monitoring strategies for clinical intervention studies 2021 · Cochrane Headline outcomes only
  OR 1.7 [1.1, 2.7]
  1 study · 4371 participants
  Moderate