What do systematic reviews say?

CHRONIC: ACEi or ARB vs placebo

It is very uncertain whether CHRONIC: ACEi or ARB changes hypotension (ARB; withdrawn from study) compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 2.6 [1.12, 6.07]
  1 study · 332 participants
  Very low

CHRONIC: ACEi or ARB vs placebo

CHRONIC: ACEi or ARB showed no clear difference in death (any cause) ( compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.85 [0.7, 1.02]
  4 studies · 5003 participants
  Low

CHRONIC: ACEi or ARB vs placebo

CHRONIC: ACEi or ARB showed no clear difference in cardiovascular death ( compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.81 [0.64, 1.01]
  2 studies · 1368 participants
  Low

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

It is very uncertain whether CHRONIC: ACEi or ARB changes heart failure hospitalisation ( compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.9 [0.43, 1.9]
  2 studies · 1368 participants
  Very low

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

Aldosterone antagonists showed no clear difference in hyperkalaemia compared with ACEi or ACEi plus ARB (low certainty).

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  RR 1.62 [0.66, 3.95]
  2 studies · 500 participants
  Low

Aldosterone antagonists vs ACEi or ACEi plus ARB

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs ACEi or ACEi plus ARB

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 465 participants
  Very low

Aldosterone antagonists vs ACEi or ACEi plus ARB

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Low