Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Emergency and Critical Care

No studies found 5 · 62.5%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 1 · 12.5%Moderate 1 · 12.5%High 0 · 0%

Confirmed SARS‐CoV‐2 infection

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Confirmed symptomatic COVID‐19b

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Severe or critical COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

All‐cause mortalityb

It is very uncertain whether booster changes all‐cause mortalityb compared with placebo/no booster (very low certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1.27 [0.52, 3.05]
1 study · 28254 participants
Very low

Systemic reactogenicity events

Booster showed no clear difference in systemic reactogenicity eventsf compared with placebo/no booster (low certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1.8 [0.71, 4.56]
1 study · 119 participants
Low

Any adverse event

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Serious adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Local reactogenicity events

Booster probably leads to higher local reactogenicity eventsf compared with placebo/no booster (moderate certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 6.46 [3.18, 13.13]
1 study · 119 participants
Moderate