Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 12.5%Moderate 0 · 0%High 7 · 87.5%

Confirmed SARS‐CoV‐2 infection

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6289 participants
High

Confirmed symptomatic COVID‐19b

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16973 participants
High

Severe or critical COVID‐19

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16976 participants
High

All‐cause mortalitye

BBV152 – Bharat Biotech showed no clear difference in all‐cause mortalitye compared with placebo (low certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 0.5 [0.17, 1.46]
1 study · 25753 participants
Low

Systemic reactogenicity events

BBV152 – Bharat Biotech leads to higher systemic reactogenicity eventsg compared with placebo (high certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1.34 [1.15, 1.58]
2 studies · 25925 participants
High

Any adverse eventi

BBV152 – Bharat Biotech showed no clear difference in any adverse eventi compared with placebo (high certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1 [0.94, 1.07]
1 study · 25753 participants
High

Serious adverse eventsi

BBV152 – Bharat Biotech leads to lower serious adverse eventsi compared with placebo (high certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 0.65 [0.43, 0.97]
1 study · 25928 participants
High

Local reactogenicity events

BBV152 – Bharat Biotech showed no clear difference in local reactogenicity eventsg compared with placebo (high certainty).

1 finding from 1 review

Efficacy and safety of COVID‐19 vaccines 2022 · Cochrane Headline outcomes only
RR 1.08 [0.95, 1.24]
2 studies · 25750 participants
High