Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 7 reviews · Eyes and Vision

No studies found 1 · 8.3%GRADE not reported 0 · 0%Very low 4 · 33.3%Low 5 · 41.7%Moderate 2 · 16.7%High 0 · 0%

Face‐down positioning vs other positioning

Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).

1 finding from 1 review

Face‐down positioning vs no face‐down positioning or posturing after macular hole surgery

Closure of macular hole · participants with idiopathic macular hole

Face‐down positioning or posturing showed no clear difference in macular hole closure (anatomical assessment) compared with no face‐down positioning or posturing after macular hole surgery (low certainty).

1 finding from 1 review

Intervention not reported

Disease progressionAssessed by: dilated assessment of the vertical C/D ratio using a 78 D lens · adults with PAC or PACG, and previous PI
1 finding from 1 review

Antibiotics vs control

Active trachoma · people (any age) with active trachoma

Antibiotic may leads to lower active trachoma Clinical assessment: active trachoma defined as TF,… compared with control (low certainty).

1 finding from 1 review

Oral vs topical antibiotics

Active trachoma · people (any age) with active trachoma

Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).

1 finding from 1 review

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Intervention not reported

3,4‐DAP (20 mg, single dose) versus placebo. Assessments made 30 minutes after taking the drug or placebo · people with acquired nystagmus
1 finding from 1 review

Intervention not reported

4‐AP (10 mg, single dose) versus 3,4‐DAP (10 mg, single dose) Assessments made at 45 and 90 minutes after taking the drug · people with acquired nystagmus
1 finding from 1 review