Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 2 reviews

No studies found 5 · 35.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 14.3%Moderate 7 · 50%High 0 · 0%

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to late AMD (neovascular AMD, geographic atrophy, or both) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to neovascular AMD · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to neovascular AMD compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to geographic atrophy · people with AMD

Antioxidant multivitamin and mineral supplement showed no clear difference in progression to geographic atrophy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to visual loss (loss of 3 or more lines on logMAR chart) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review