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What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Kidney and Transplant

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- Amphotericin B deoxycholate vs liposomal amphotericin B: effects on kidney function · Increase in SCr level: ≥ two‐fold from baseline level SCr level (mg/dL)
  Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function 2015 · Cochrane Headline outcomes only
  RR 0.49 [0.4, 0.59]
  10 studies · 2172 participants
  Moderate

Amphotericin B deoxycholate vs liposomal amphotericin B: effects on kidney function

Increase in SCr level: ≥ two‐fold from baseline level SCr level (mg/dL) · patients in treatment with amphotericin B

Amphotericin B deoxycholate probably leads to lower increase in SCr level: ≥ two‐fold from baseline level SCr level… compared with liposomal amphotericin B: effects on kidney function (moderate certainty).

1 finding from 1 review

Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function 2015 · Cochrane Headline outcomes only
RR 0.49 [0.4, 0.59]
10 studies · 2172 participants
Moderate