Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer · Headline outcomes only

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No studies found 2 · 50%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Amifostine vs no intervention

Mean GI symptom scores · People with urological, gynaecological or colorectal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amifostine vs no intervention

Acute and late GI toxicity (grade 2+) · People with urological, gynaecological or colorectal cancer

Summary of findings: Amifostine may leads to lower acute and late GI toxicity (grade 2+) compared with no intervention (low certainty).

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
RR 0.25
3 studies · 278 participants
Low

Amifostine vs no intervention

Diarrhoea (grade 2+) · People with urological, gynaecological or colorectal cancer

It is very uncertain whether summary of findings: Amifostine changes diarrhoea (grade 2+) during treatment compared with no intervention (very low certainty).

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
RR 0.25 [0.06, 0.98]
1 study · 36 participants
Very low

Amifostine vs no intervention

QoL · People with urological, gynaecological or colorectal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found