Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 1 · 14.3%GRADE not reported 1 · 14.3%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Aggressive vs conservative blood transfusion

All‐cause mortality · people with SCD

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 230 participants
GRADE not reported

Aggressive vs conservative blood transfusion

Serious complications related to SCD ‐ cholecystectomy ACS · people with SCD

It is very uncertain whether aggressive changes serious complications related to SCD ‐ cholecystectomy ACS compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.84 [0.38, 1.84]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Serious complications related to SCD ‐ cholecystectomy painful crisis · people with SCD

It is very uncertain whether aggressive changes serious complications related to SCD ‐ cholecystectomy painful crisis compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.3 [0.09, 1.04]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Serious infection ‐ cholecystectomy · people with SCD

It is very uncertain whether aggressive changes serious infection ‐ cholecystectomy compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.75 [0.59, 5.18]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Perioperative complications ‐ cholecystectomy complications (any) · people with SCD

It is very uncertain whether aggressive changes perioperative complications ‐ cholecystectomy complications (any) compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.75 [0.36, 1.55]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Transfusion‐related complications ‐ cholecystectomy complications (any) · people with SCD

It is very uncertain whether aggressive changes transfusion‐related complications ‐ cholecystectomy complications… compared with conservative blood transfusion (very low certainty).

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.85 [0.89, 3.88]
1 study · 230 participants
Very low

Aggressive vs conservative blood transfusion

Quality of life · people with SCD

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found