Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 34 findings · 5 reviews · Eyes and Vision

No studies found 6 · 17.6%GRADE not reported 0 · 0%Very low 10 · 29.4%Low 12 · 35.3%Moderate 5 · 14.7%High 1 · 2.9%

Wavefront procedures vs conventional procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment:12 months ‐ Procedure PRK · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment‐procedure LASIK; Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor; proportion of eyes wi... · Adults with refractive errors

The review found no eligible studies for this question.

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

NSAIDs vs placebo or active control

Visual improvement at end of treatment, as defined by two or more Snellen lines · participants with acute CME (< 4 months) following cataract surgery

It is very uncertain whether NSAID changes visual improvement at end of treatment, as defined by two or more… compared with placebo or active control (very low certainty).

1 finding from 1 review

NSAIDs vs active control

Visual improvement at end of treatment, as defined by two or more Snellen lines · participants with acute or chronic CME following cataract surgery

It is very uncertain whether NSAID changes visual improvement at end of treatment, as defined by two or more… compared with active control (very low certainty).

1 finding from 1 review