Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews · Gynaecology and Fertility · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 1 · 25%High 0 · 0%

Awareness of prolapse · vaginal prolapse

Transvaginal permanent mesh probably leads to lower awareness of prolapse (0.5 to 7 years) compared with native tissue repair (moderate certainty).

1 finding from 1 review

Transvaginal mesh or grafts or native tissue repair for vaginal prolapse 2024 · Cochrane Headline outcomes only
RR 0.83 [0.73, 0.95]
17 studies · 2932 participants
Moderate

Need for repeat surgery · vaginal prolapse

Transvaginal permanent mesh may leads to higher repeat surgery (0.5 to 7 years) compared with native tissue repair (low certainty).

1 finding from 1 review

Transvaginal mesh or grafts or native tissue repair for vaginal prolapse 2024 · Cochrane Headline outcomes only
RR 1.56 [1.07, 2.26]
27 studies · 3916 participants
Low

Hot flush frequency (number/day) · women with hot flushes

Oral beta‐estradiol showed no clear difference in frequency of hot flushes Oral beta‐estradiol 0.5‐1.0 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 356 participants
Low

Adverse effects Oral beta‐estradiol 0.5‐2.0 mg/day · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 433 participants
Low