Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,061 questions · 2,151 findings · 116 reviews

No studies found 609 · 28.3%GRADE not reported 268 · 12.5%Very low 635 · 29.5%Low 491 · 22.8%Moderate 122 · 5.7%High 26 · 1.2%

Psychological therapy vs Waitlist/Usual Care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy probably leads to lower acceptability 1 ‐ proportion of participants withdrawing during… compared with usual care or waiting list (moderate certainty).

1 finding from 1 review

Psychological therapy vs Waitlist/Usual Care

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy may leads to higher treatment response at end of treatment CGI‐improvement/Global… compared with usual care or waiting list (low certainty).

1 finding from 1 review

Psychological therapy vs enhanced or structured care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy showed no clear difference in acceptability 1 ‐ proportion of participants withdrawing during… compared with enhanced or structured care (moderate certainty).

1 finding from 1 review

Electrostimulation (device) vs Placebo (sham/placebo device)

Dry mouth (xerostomia) · Adults with dry mouth due to Sjogren's Syndrome
1 finding from 1 review

Acupuncture vs sham

Unstimulated whole saliva (UWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome

Acupuncture may leads to higher unstimulated whole saliva (UWS) compared with placebo (sham acupuncture) (low certainty).

2 findings from 1 review

Electrostimulation (device) vs Placebo (sham/placebo device)

Stimulated whole saliva (SWS) · Adults with dry mouth due to Sjogren's Syndrome

It is very uncertain whether electrostimulation (device) changes stimulated whole saliva (SWS) compared with placebo (sham/placebo device) (very low certainty).

1 finding from 1 review

Acupuncture vs sham

Stimulated whole saliva (SWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome

Acupuncture may leads to higher stimulated whole saliva (SWS) compared with placebo (sham acupuncture) (low certainty).

2 findings from 1 review