Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Indomethacin showed no clear difference in oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol led to lower oral mucositis (any severity) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Cryotherapy (ice chips) may leads to lower oral mucositis (any severity) compared with no treatment (low certainty).
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Prednisone showed no clear difference in oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Laser (low level) led to lower oral mucositis (severe) compared with placebo/sham/no treatment; GRADE not reported.
1 finding from 1 review
RR 0.2 [0.06, 0.62]
2 studies
GRADE not reported
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Camomile showed no clear difference in oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Glutamine showed no clear difference in oral mucositis (severe) compared with placebo/usual care; GRADE not reported.
1 finding from 1 review
RR 0.69 [0.37, 1.29]
5 studies
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)
Cognitive (behavioural) therapy led to lower burning mouth pain intensity (6-month follow-up) compared with attention placebo; GRADE not reported.
1 finding from 1 review
SMD -2.79 [-3.83, -1.75]
1 study
GRADE not reported
Burning mouth pain intensity (post-treatment) · Adults over 18 years of age with chronic orofacial pain (burning mouth syndrome)
Cognitive (behavioural) therapy led to lower burning mouth pain intensity (post-treatment) compared with attention placebo; GRADE not reported.
1 finding from 1 review
SMD -2.40 [-3.40, -1.40]
1 study
GRADE not reported
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Keratinocyte GF may leads to lower oral mucositis (any severity) compared with placebo (low certainty).
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Laser (low level) led to lower oral mucositis (severe) compared with povidone; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Acyclovir showed no clear difference in oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Cryotherapy (ice chips) 30 minutes showed no clear difference in oral mucositis (severe) compared with cryotherapy (ice chips) 60 minutes; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Superoxide dismutase showed no clear difference in oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Histamine gel showed no clear difference in oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Camomile showed no clear difference in oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chinese herbs (medicine) led to lower oral mucositis (any severity) compared with control (Dobell's solution); GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Keratinocyte GF 50 mg showed no clear difference in oral mucositis (moderate to severe) compared with keratinocyte GF 25 mg; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Keratinocyte GF 50 mg showed no clear difference in oral mucositis (severe) compared with keratinocyte GF 25 mg; GRADE not reported.
1 finding from 1 review
Head circumference (mm) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
Squeezable (modified) feeding bottle led to lower head circumference (cm) compared with rigid feeding bottle; GRADE not reported.
1 finding from 1 review