Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 13,493 findings · 1,305 reviews · Headline outcomes only

No studies found 2,594 · 19.2%GRADE not reported 728 · 5.4%Very low 2,868 · 21.3%Low 3,777 · 28%Moderate 2,620 · 19.4%High 906 · 6.7%

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Music therapy vs placebo or usual care

Adverse events Any serious or non‐serious adverse event · Individuals with autism spectrum disorder

Music therapy showed no clear difference in adverse events Any serious or non‐serious adverse event compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability scale used in the original study · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants with an improvement in disability scale… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement of muscle strength · people with multifocal motor neuropathy

IVIg may leads to higher proportion of participants with an improvement of muscle strength compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability at 12 months or later · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Proportion of participants in which at least 1 conduction block resolved after therapy · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants in which at least 1 conduction block… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of IVIg‐treated participants with an increase in disability during controlled IVIg withdrawal · people with multifocal motor neuropathy

IVIg probably leads to higher proportion of IVIg‐treated participants with an increase in… compared with placebo (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of IVIg‐treated participants with a decrease in muscle strength during controlled IVIg withdrawal · people with multifocal motor neuropathy

IVIg probably leads to lower proportion of IVIg‐treated participants with a decrease in muscle… compared with placebo (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with side effects attributable to treatment · people with multifocal motor neuropathy

It is very uncertain whether IVIg changes proportion of participants with side effects attributable to treatment compared with placebo (very low certainty).

1 finding from 1 review