Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Glutaraldehyde + zinc oxide and eugenol (ZOE) vs Full strength formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + zinc oxide and eugenol (ZOE) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Diode laser vs Formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser showed no clear difference in clinical failure compared with formocresol (FC); GRADE not reported.

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review