Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,954 questions · 2,335 findings · 149 reviews · All outcomes

No studies found 436 · 18.7%GRADE not reported 1,370 · 58.7%Very low 254 · 10.9%Low 173 · 7.4%Moderate 80 · 3.4%High 22 · 0.9%

Tap water irrigation (monoject syringe) vs No rinsing

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Tap water irrigation (monoject syringe) led to lower presence of dry socket compared with no rinsing; GRADE not reported.

1 finding from 1 review

Chlorhexidine gel vs Chlorhexidine, 0.2% to 2% (solution or gel)

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Chlorhexidine gel 1% showed no clear difference in presence of dry socket compared with chlorhexidine gel 0.2%; GRADE not reported.

1 finding from 1 review

Honey (Manuka, topical) vs Chlorhexidine rinse (0.2%)

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Honey (Manuka, topical) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%); GRADE not reported.

1 finding from 1 review

Chlorhexidine gel (0.2%, intrasocket) vs placebo or no treatment

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Chlorhexidine gel (0.2%, intrasocket) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Artemisia desertorum spreng (Shahaosan) vs Artemisia desertorum spreng (Yunnan)

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with artemisia desertorum spreng (Yunnan); GRADE not reported.

1 finding from 1 review

Acupuncture at P6 point vs sham

Reduction in gagging (assessor-reported – treatment effectiveness) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

Acupuncture at P6 point showed no clear difference in reduction in gagging (assessor-reported – treatment effectiveness) compared with sham acupuncture; GRADE not reported.

1 finding from 1 review

Acupressure at P6 point with thumb vs sham

Completion of dental treatment · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupressure at P6 point with thumb changes completion of dental procedure compared with sham (dummy) acupressure (very low certainty).

1 finding from 1 review

Acupuncture at P6 point vs sham

Successful completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupuncture at P6 point changes successful completion of dental procedure compared with sham acupuncture (very low certainty).

1 finding from 1 review

Acupressure at P6 point with sea band plus sedation vs Sham (dummy) acupressure with sedation

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Acupressure at P6 point with sea band vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation

Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupressure at P6 point with device plus sedation changes reduction in gagging (patient-reported) compared with sham (dummy) acupressure with sedation (very low certainty).

1 finding from 1 review

Acupressure at P6 point with thumb plus sedation vs Sham (dummy) acupressure with sedation

Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupressure at P6 point with thumb plus sedation changes reduction in gagging (patient-reported) compared with sham (dummy) acupressure with sedation (very low certainty).

1 finding from 1 review

Acupuncture at P6 point vs sham

Reduction in gagging (patient-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupuncture at P6 point changes reduction in gagging (patient-reported – ordinal converted to… compared with sham acupuncture (very low certainty).

2 findings from 1 review

Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation

Completion of dental treatment · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

It is very uncertain whether acupressure at P6 point with device plus sedation changes completion of dental procedure compared with sham (dummy) acupressure with sedation (very low certainty).

1 finding from 1 review

Acupuncture at P6 point vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
1 finding from 1 review
  • Adverse effects: 33 participants (1 RCT, Zotelli 2014); very low certainty. The trial authors were unsure whether the reported adverse events (one control participant reported increased sweating) were due to…
    1 study · 33 participants
    Very low

Acupressure at P6 point with sea band plus sedation vs Sham (dummy) acupressure with sedation

Presence or absence of gagging · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review