Intervention not reported
Persistence · people with glaucoma or ocular hypertension
1 finding from 1 review
Intervention not reported
Mortality 4 to 5 years · Adults with mild hypertension and no cardiovascular disease
It is very uncertain whether the intervention changes mortality 4 to 5 years (very low certainty).
1 finding from 1 review
Intervention not reported
Total CV events 5 years · Adults with mild hypertension and no cardiovascular disease
It is very uncertain whether the intervention changes total CV events 5 years (very low certainty).
1 finding from 1 review
Intervention not reported
Withdrawals due to adverse effects 5 years · Adults with mild hypertension and no cardiovascular disease
The intervention probably leads to higher withdrawals due to adverse effects 5 years (moderate certainty).
1 finding from 1 review
Quit at longest · individuals who smoke cigarettes and are admitted to a hospital for medical or surgical care
It is very uncertain whether smoking cessation counselling changes quit at longest compared with no smoking cessation counselling, grouped by intensity of intervention (very low certainty).
4 findings from 1 review
RR 1.52 [0.8, 2.89]
2 studies · 1417 participants
Very low
RR 1.27 [1.02, 1.58]
12 studies · 4432 participants
Moderate
RR 1.04 [0.9, 1.2]
7 studies · 4627 participants
Very low
Show 1 more finding
Recurrence · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes recurrence rate compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Wound infection · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound infection compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Wound dehiscence · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound dehiscence compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Return to work · pilonidal sinus
1 finding from 1 review
Quality of life ‐ not reported · pilonidal sinus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to complete healing · pilonidal sinus
1 finding from 1 review
Proportion of wounds healed · pilonidal sinus
Summary of findings table ‐ Off‐midline closure may leads to higher proportion of wounds healed compared with tension‐free midline closure (low certainty).
1 finding from 1 review
Intervention not reported
Total studies: 42 Total participants: 14,626 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
The intervention led to lower total studies: 42 Total participants: 14,626; GRADE not reported.
1 finding from 1 review
no estimate extracted
42 participants
GRADE not reported
Intervention not reported
Desvenlafaxine high dose RCTs: 2 Participants: 870 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
2 participants
Very low
Intervention not reported
Total studies: 50 Total participants: 14,926 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
50 participants
GRADE not reported
Intervention not reported
Duloxetine high dose RCTs: 14 Participants: 3683 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
14 participants
Low
Intervention not reported
Duloxetine standard dose RCTs: 18 Participants: 4959 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
18 participants
Moderate
Intervention not reported
Milnacipran high dose RCTs: 2 Participants: 1670 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
2 participants
Low
Intervention not reported
Milnacipran standard dose RCTs: 4 Participants: 1866 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
4 participants
Moderate
Intervention not reported
Duloxetine low dose RCTs: 6 Participants: 1104 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
6 participants
Moderate