Depression remission · older people with depression
1 finding from 1 review
Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
1 finding from 1 review
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
1 finding from 1 review
Specific behaviour ‐ agitation · people with dementia
1 finding from 1 review
Quality of life (self‐rating by the participants; · people with dementia
1 finding from 1 review
Quality of life (proxy‐rating; · people with dementia
1 finding from 1 review
Adverse events; · people with dementia
1 finding from 1 review
Positive affect ( · people with dementia
1 finding from 1 review
Negative affect ( · people with dementia
1 finding from 1 review
Mood · people with dementia
1 finding from 1 review
Outcomes (weighted · stable COPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Moderate‐to‐severe exacerbations (rate) · stable COPD
Triple therapy may leads to lower moderate‐to‐severe exacerbations (rate) compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Severe exacerbations (rate) · stable COPD
Triple therapy may leads to lower severe exacerbations (rate) compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Respiratory HRQoL measured by SGRQ, ≥ 4‐point decrease from baseline (lower scores indicate better HRQoL) · stable COPD
Triple therapy leads to higher respiratory HRQoL measured by SGRQ, ≥ 4‐point decrease from baseline… compared with LABA/LAMA combination (high certainty).
1 finding from 1 review
Pneumonia (labelled as an SAE) · stable COPD
Triple therapy probably leads to higher pneumonia (labelled as an SAE) compared with LABA/LAMA combination (moderate certainty).
1 finding from 1 review
SAEs · stable COPD
Triple therapy showed no clear difference in all‐cause SAEs compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Symptoms of dyspnoea · stable COPD
Triple therapy probably leads to higher symptom score TDI, ≥ 1‐unit increase (lower scores indicate worse… compared with LABA/LAMA combination (moderate certainty).
1 finding from 1 review
Change in baseline trough FEV1 · stable COPD
Triple therapy may leads to higher lung function, change in trough FEV1 (mL) compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Mortality (all‐cause) · stable COPD
Triple therapy may leads to lower mortality (all‐cause) compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Intervention not reported
Total studies: 17 RCTs Total participants: 22,819 · adolescents and adults with uncontrolled asthma, despite being on medium‐dose ICS Interventions: HD‐ICS, LD‐ICS/LABA, MD‐ICS/LAMA,…
1 finding from 1 review