Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Intervention not reported

Beta‐blockers plus Sclerotherapy(1 RCT; 40 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding

It is very uncertain whether the intervention changes beta‐blockers plus Sclerotherapy(1 RCT; 40 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus sclerotherapy(4 RCTs; 231 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention probably leads to lower beta‐blockers plus sclerotherapy(4 RCTs; 231 participants) (moderate certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Sclerotherapy(8 RCTs; 370 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Sclerotherapy(8 RCTs; 370 participants) (low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Mortality (at the end of · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes mortality (at the end of compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review