Serious adverse events at up to day 28 · non‐hospitalised adults with mild COVID‐19
Remdesivir and standard care may leads to lower serious adverse events at up to day 28 compared with standard care (plus/minus placebo) (low certainty).
1 finding from 1 review
Adverse events: all grades · non‐hospitalised adults with mild COVID‐19
Remdesivir and standard care showed no clear difference in adverse events (any grade) at up to day 28 compared with standard care (plus/minus placebo) (moderate certainty).
1 finding from 1 review
All‐cause mortality at up to day 60 · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care showed no clear difference in all‐cause mortality at up to day 60 compared with standard care (plus/minus placebo) (moderate certainty).
1 finding from 1 review
In‐hospital mortality at up to day 150 · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care showed no clear difference in in‐hospital mortality at up to day 150 compared with standard care (plus/minus placebo) (moderate certainty).
1 finding from 1 review
Clinical improvement: discharged alive ( · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care probably leads to higher clinical improvement: participants alive and ready to be discharged… compared with standard care (plus/minus placebo) (moderate certainty).
1 finding from 1 review
Clinical worsening: new need for invasive mechanical ventilation or death · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care probably leads to lower clinical worsening: time to new need for invasive mechanical… compared with standard care (plus/minus placebo) (moderate certainty).
1 finding from 1 review
Adverse events: all grades · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care showed no clear difference in adverse events (any grade) at up to day 28 compared with standard care (plus/minus placebo) (low certainty).
1 finding from 1 review
Serious adverse events at up to day 28 · hospitalised individuals with COVID‐19 (moderate to severe disease)
Remdesivir and standard care showed no clear difference in serious adverse events at up to day 28 compared with standard care (plus/minus placebo) (low certainty).
1 finding from 1 review
All‐cause mortality at up to day 28 · non‐hospitalised adults with mild COVID‐19
1 finding from 1 review
Clinical improvement: participants with symptom alleviation at up to day 14 · non‐hospitalised adults with mild COVID‐19
It is very uncertain whether remdesivir and standard care changes clinical improvement: participants with symptom alleviation at up to… compared with standard care (plus/minus placebo) (very low certainty).
1 finding from 1 review
Pain (PIPP) · procedural pain in neonates
3 findings from 1 review
Parent satisfaction with care provided in the NICU—not reported · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
Pain, assessed using the DAN pain scale, ranging from 0 to 21, 1 to 2 hours after procedure · procedural pain in neonates
1 finding from 1 review
Pain, assessed using the CRIES pain scale, ranging from 0 to 10, during the procedure— opioids versus facilitated tucking · procedural pain in neonates
1 finding from 1 review
Any harms ‐ severe apnea requiring resuscitation · procedural pain in neonates
It is very uncertain whether opioids changes any harms ‐ severe apnea requiring resuscitation compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of bradycardia · procedural pain in neonates
It is very uncertain whether opioids changes episodes of bradycardia compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of apnea · procedural pain in neonates
Opioids may leads to higher episodes of apnea compared with no treatment/placebo (low certainty).
1 finding from 1 review
Hypotension · procedural pain in neonates
1 finding from 1 review
Outcome№ of participants(studies) · children with acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relief of pain · children with acute postoperative pain
2 findings from 1 review
no estimate extracted
50 participants
GRADE not reported
no estimate extracted
50 participants
GRADE not reported