Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Electrofulguration + calcium hydroxide (CH) showed no clear difference in clinical failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Erbium:YAG laser led to lower radiological failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide + sodium hypochlorite (NaOCl) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Vitapex (calcium hydroxide/iodoform) may leads to higher radiological failure compared with zinc oxide and eugenol (ZOE) (low certainty).
1 finding from 1 review
Biodentine vs Diode laser
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; RR 2.00 (0.20 to 20.33)
1 study · 40 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide/iodoform (CH/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Metapex (calcium hydroxide/iodoform) vs RC Fill (ZOE with iodoform)
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, radiolucency, root resorption, filling material anomaly (Ramar 2010); no significant differences
1 study · 64 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
2 findings from 1 review
No clinical failure in any participant (Malekafzali 2011); not estimable
1 study · 80 participants
GRADE not reported
RR 3.00 [0.13, 69.70]
1 study · 42 participants
Very low
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Biodentine showed no clear difference in clinical failure compared with tempophore; GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Total mortality · adults with primary hypertension
1 finding from 1 review
Withdrawals due to adverse events · adults with primary hypertension
1 finding from 1 review
Total mortality · adults with primary hypertension
First‐line beta‐blocker showed no clear difference in total mortality compared with placebo (moderate certainty).
1 finding from 1 review
Stroke · adults with primary hypertension
First‐line beta‐blocker may leads to lower total stroke compared with placebo (low certainty).
1 finding from 1 review
Total coronary heart disease · adults with primary hypertension
First‐line beta‐blocker showed no clear difference in total coronary heart disease compared with placebo (low certainty).
1 finding from 1 review
Cardiovascular events · adults with primary hypertension
First‐line beta‐blocker may leads to lower total cardiovascular events compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults with primary hypertension
First‐line beta‐blocker may leads to higher withdrawal due to adverse effects compared with placebo (low certainty).
1 finding from 1 review
Stroke · adults with primary hypertension
1 finding from 1 review