Implant failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower implant failure compared with no augmentation; GRADE not reported.
1 finding from 1 review
Aesthetics · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by dentist (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
After placement of the final restorations the operator judged aesthetics to be poor in 2/10 patients of the Bio-Oss group and in 4/10 of the Bio-Oss plus barrier group; no statistically significant difference.
1 study · 20 participants
GRADE not reported
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.
1 finding from 1 review
Four complications occurred: two dehiscences in the resorbable group; one abscess and one dehiscence in the resorbable + autogenous bone group; none in the non-resorbable group. No statistically significant differences…
1 study · 23 participants
GRADE not reported
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower major complications at the implant/donor site compared with no augmentation; GRADE not reported.
1 finding from 1 review
Two complications occurred in the group treated with autogenous bone (one abscess that determined the early failure of the implant and one wound dehiscence); none in the control group.
1 study · 26 participants
GRADE not reported
Measures of behaviour during local anaesthesia administration (undesirable behaviours: crying, hand movement, physical resistance, leg movement) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
Patients who were hypnotised demonstrated fewer undesirable behaviours (crying, hand movement, physical resistance and leg movement) than those who did not undergo hypnosis. Decreased crying with hypnosis was the only…
1 study · 29 participants
GRADE not reported
Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (vertical - VDH) compared with no augmentation; GRADE not reported.
1 finding from 1 review
Both treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the two procedures for vertical height of the defect (VDH) (Chen 2005b).
1 study · 26 participants
GRADE not reported
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Morphine led to lower average pain scores (0-100 VAS) compared with tricyclic antidepressant (nortriptyline); GRADE not reported.
1 finding from 1 review
Poor aesthetics measured by patient (after restoration) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by patient (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (horizontal - HDD) compared with no augmentation; GRADE not reported.
1 finding from 1 review
Augmentation (prosthesis/implant) failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower augmentation (prosthesis/implant) failure compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Poor aesthetics measured by dentist (3 years) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by dentist (3 years) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
After 3 years of loading, the operator judged aesthetics to be poor in 2/7 patients of the Bio-Oss group and in 2/5 of the Bio-Oss plus barrier group; no statistically significant difference.
1 study · 20 participants
GRADE not reported
Occlusal splint vs Pharmacological interventions (benzodiazepines, anticonvulsants, beta blockers, dopamine agents, antidepressants, botulinum toxin A and B, analgesics)
Outcome not reported · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis clinical,…
The review found no eligible studies for this question.
1 finding from 1 review
Clinical failure (post dislodgement) · Participants with endodontically-treated permanent premolars restored with a carbon-fibre post (Category III)
Direct composite restoration (final restoration) showed no clear difference in clinical failure (post dislodgement) compared with full-coverage metal-ceramic crown; GRADE not reported.
1 finding from 1 review
Gingivitis · Adults, 16 years and older (dentate)
It is very uncertain whether interdental brushing plus toothbrushing changes gingivitis (gingival index) compared with toothbrushing alone (very low certainty).
MD -0.53 [-0.83, -0.23]
1 study · 62 participants
Very low
MD -0.05 [-0.13, 0.03]
1 study · 31 participants
Very low
MD -0.53 [-0.83, -0.23]
1 study · 62 participants
Very low
Plaque · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing may leads to lower plaque compared with toothbrushing alone (low certainty).
Gingivitis · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing may leads to lower gingivitis (proportion of bleeding sites) compared with flossing plus toothbrushing (low certainty).
MD -0.06 [-0.08, -0.03]
6 studies · 234 participants
Low
SMD -0.40 [-0.70, -0.11]
3 studies · 183 participants
Low
SMD -0.53 [-0.81, -0.24]
7 studies · 326 participants
Low
Show 1 more finding
Plaque · Adults, 16 years and older (dentate)
It is very uncertain whether interdental brushing plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).
SMD -0.47 [-0.84, -0.11]
5 studies · 290 participants
Very low
SMD 0.10 [-0.13, 0.33]
7 studies · 326 participants
Low
SMD -2.14 [-5.25, 0.97]
2 studies · 107 participants
Very low
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Side effects · Adults, 16 years and older (dentate)
Harms and adverse outcomes (SoF): Neither study reported any information about adverse events. Jared 2005 assessed adverse events (participants issued a symptom diary) but did not report the findings; Graziani 2017 did…
1 study
GRADE not reported
Not estimable. Only 1 study reported adverse outcomes in terms of problems with the use of the assigned interdental cleaning aids. (See comment) In this comparison the single study (Jared 2005) asked participants to…
1 study
GRADE not reported