Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Transdermal oestrogens vs oral oestrogens

Clinical pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

Transdermal oestrogens showed no clear difference in clinical pregnancy rate compared with oral oestrogens (low certainty).

1 finding from 1 review

LNG‐IUS vs another combined low‐dose OCP

Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids
2 findings from 1 review

LNG‐IUS vs oral progestogen (norethisterone acetate)

Change in haemoglobin level from baseline · women with uterine fibroids
2 findings from 1 review