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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

612 questions in 46 reviews · Work

current versions
No studies 78 · 12.7%Ungraded 4 · 0.7%Very low 295 · 48.2%Low 182 · 29.7%Moderate 49 · 8%High 4 · 0.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Morning bright light vs afternoon bright light
Alertness · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
MD 71 study · 30 participantsLow
Morning bright light vs afternoon bright light
Mood · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
RR 1.6 [0.81, 3.2]1 study · 30 participantsLow
Morning bright light vs afternoon bright light
Adverse events (frequency) · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
RR 0.53 [0.26, 1.07]1 study · 30 participantsLow
High correlated colour temperature light vs standard illumination
Mood (positive) · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted94 participantsVery low
High correlated colour temperature light vs standard illumination
Mood (negative) · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted94 participantsVery low
High correlated colour temperature light vs standard illumination
Adverse events ‐ eye discomfort · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted94 participantsVery low
Indirect light vs direct light
Alertness · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extractedNRNo studies
Indirect light vs direct light
Mood · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted1 study · 22 participantsLow
Indirect light vs direct light
Adverse events (ocular problems) · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted1 study · 22 participantsLow
Individually applied blue‐enriched light vs no treatment
Alertness · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted1 study · 25 participantsVery low
Individually applied blue‐enriched light vs no treatment
Mood · daytime workers
Workplace lighting for improving alertness and mood in daytime workers (2018) · Cochrane
no estimate extracted1 study · 25 participantsVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Cyclophosphamide alone · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.83 [0.46, 1.52]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Cytarabine · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.72 [0.18, 2.86]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Gemcitabine · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.96 [0.6, 1.54]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir, epirubicin, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Patient‐care areas · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
5‐fluorouracil, cytarabine, gemcitabine, irinotecan, docetaxel, paclitaxel, vinorelbine, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Cyclophosphamide‡ · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Epirubicin · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
5‐fluorouracil, cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Other measures of contamination · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
Cyclophosphamide or ifosfamide · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.09 [0, 2.79]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Health outcomes · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
Adverse events · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
Potential cost savings · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Cyclophosphamide, ifosfamide, or gemcitabine · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Other measures of exposure · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
Pharmacy areas · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
no estimate extractedNRNo studies
Closed‐system transfer device plus safe handling vs safe handling alone
Cyclophosphamide · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.89 [0.78, 1.01]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Ifosfamide · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.94 [0.74, 1.19]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
Methotrexate · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.84 [0.58, 1.22]NRVery low
Closed‐system transfer device plus safe handling vs safe handling alone
5‐fluorouracil · healthcare staff who handle infusional hazardous drugs
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for… (2018) · Cochrane
RR 0.63 [0.42, 0.94]NRVery low
Intervention NR
Immediate change in level in year 2000 (noise level at work as PEL dose in dB(A); range 0 to 6400, log scale) · workers with noise exposure
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extractedNRVery low
Hearing loss prevention programme (HLPP) vs non‐exposed workers (hearing loss)
Hearing loss Change in hearing threshold at 4 kHz in dB · workers
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extracted3 studies · 1846 participantsVery low
Intervention NR
Change in slope after introduction (noise level at work as PEL dose in dB(A); range 0 to 6400, log scale) · workers with noise exposure
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extractedNRVery low
Earplugs with instruction vs without instruction (noise exposure)
Mean noise attenuation over 0.5, 1, 2, 3, 4, 6, 8 kHz (dB) Immediate · workers with exposure to noise
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extracted2 studies · 140 participantsModerate
Training plus exposure information vs training (noise exposure)
Change in noise levels at 4 months' · workers exposed to noise
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extracted1 study · 176 participantsLow
Earmuffs vs earplugs (hearing loss)
Hearing loss change over 3 years (4 kHz/STS) · workers exposed to 88‐94 dB(A)
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
OR 0.8 [0.63, 1.03]3242 participantsVery low
Hearing loss prevention programme vs audiometric testing (hearing loss)
Hearing loss STS ≥ 10 dB loss average over 2, 3, 4 kHz in either ear · agricultural students without hearing loss
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
OR 0.85 [0.29, 2.44]1 study · 687 participantsModerate
Hearing loss prevention programme vs audiometric testing (hearing loss)
Hearing loss STS ≥ 10 dB hearing loss average over 2, 3, 4 kHz in either ear · agricultural students without hearing loss
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
OR 0.94 [0.46, 1.91]1 study · 355 participantsModerate
Hearing loss prevention programme (HLPP) with exposure information vs HLPP without exposure information (hearing loss)
Annual increase in hearing threshold (dB/year at 2,3 and 4 kHz) · workers exposed to noise
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
no estimate extracted312 participantsVery low
Well‐implemented hearing loss prevention programme (HLPP) vs less well‐implemented HLPP (hearing loss)
Hearing loss STS > 10 dB change average over 2, 3 and 4 kHz1 · workers
Interventions to prevent occupational noise‐induced hearing loss (2017) · Cochrane
OR 0.4 [0.23, 0.69]3 studies · 16301 participantsVery low
Cognitive rehabilitation vs no treatment
Return to work Assessed by attainment of work within 14 weeks (medium‐term) of initiating intervention · traumatic brain injury ‐ mild, moderate or severe
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
RR 1.8 [0.74, 4.39]1 study · 50 participantsVery low
Cognitive didactic therapy vs functional experiential therapy
Independence in ADL Structured interview · adult veterans or active duty military service personnel with moderate‐to‐severe traumatic brain injury
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
RR 0.9 [0.75, 1.08]1 study · 366 participantsLow
Cognitive rehabilitation vs no treatment
Community integration · traumatic brain injury ‐ mild, moderate or severe
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
no estimate extracted1 study · 12 participantsLow
Cognitive rehabilitation vs no treatment
Quality of life · traumatic brain injury ‐ mild, moderate or severe
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
no estimate extracted1 study · 98 participantsLow
Cognitive rehabilitation vs conventional treatment
Return to work Return to work status · people with traumatic brain injury
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
RR 1.43 [0.87, 2.33]1 study · 68 participantsLow
Cognitive rehabilitation vs conventional treatment
Independence in ADL FIM, with 18 items in basic and psychosocial functional activities. Score ranges from 0 to 126; higher scores indicate higher functional independence. Assessment of motor and process skills, score ranges from 4 to 144; higher s... · people with traumatic brain injury
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
no estimate extracted2 studies · 41 participantsVery low
Cognitive rehabilitation vs conventional treatment
Community integration Community Integration Questionnaire. Score ranges from 0 to 29, higher scores indicate better community integration. · people with traumatic brain injury
Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes (2017) · Cochrane
no estimate extracted3 studies · 123 participantsLow