Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

199 questions · 201 findings · 12 reviews · Pregnancy and Childbirth

No studies found 55 · 27.4%GRADE not reported 8 · 4%Very low 29 · 14.4%Low 57 · 28.4%Moderate 47 · 23.4%High 5 · 2.5%

Summary of findings table ‐ Midwife continuity models vs other models of care

Intact perineum · childbearing women and their infants (all) (important/secondary outcomes)

Summary of findings table ‐ Midwife continuity of care models showed no clear difference in intact perineum compared with other models of care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Midwife continuity models vs other models of care

Fetal loss at or after 24 weeks gestation · childbearing women and their infants (all) (important/secondary outcomes)

It is very uncertain whether summary of findings table ‐ Midwife continuity of care models changes fetal loss at or after 24 weeks gestation compared with other models of care (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Midwife continuity models vs other models of care

Preterm birth · childbearing women and their infants (all) (important/secondary outcomes)

Summary of findings table ‐ Midwife continuity of care models showed no clear difference in preterm birth (< 37 weeks) compared with other models of care (low certainty).

1 finding from 1 review

Summary of findings table ‐ Midwife continuity models vs other models of care

Neonatal death (baby born alive at any gestation and dies within 28 days) · childbearing women and their infants (all) (important/secondary outcomes)

It is very uncertain whether summary of findings table ‐ Midwife continuity of care models changes neonatal death (baby born alive at any gestation and dies within 28… compared with other models of care (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Fetal/neonatal/infant · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A1: Fetal or neonatal or infant death (< 1 year of age) – all… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Respiratory distress syndrome · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid leads to lower A5: Respiratory distress syndrome – all fetuses randomised compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

A7: Severe lung disease – all fetuses randomised · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A7: Severe lung disease – all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Chronic lung disease · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A8: Chronic lung disease – all fetuses randomised compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Intraventricular haemorrhage, Papile grade 3/4 · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A9: Severe intraventricular haemorrhage (grade 3 or 4) – all fetuses… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Necrotising enterocolitis · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A11: Necrotising enterocolitis – all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

A12: Composite of serious outcomes– all fetuses randomised · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A12: Composite of serious outcomes– all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

B3: Caesarean section – an all women · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B3: Caesarean section – an all women compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C1: Total deaths (after randomisation) up to early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C1: Total deaths (after randomisation) up to early childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C2: Neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C2: Neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C3: Survival free of neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C3: Survival free of neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C4: Survival free of major neurodevelopmental impairment atearly childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C4: Survival free of major neurodevelopmental impairment atearly… compared with single course (moderate certainty).

1 finding from 1 review