What do systematic reviews say?

Moxifloxacin vs amoxicillin‐clavulanate

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 54 participants
  Very low

Moxifloxacin vs amoxicillin‐clavulanate

The review found no eligible studies for this question.

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

AB103 vs placebo

It is very uncertain whether AB103 changes mortality compared with placebo (very low certainty).

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  RR 0.34 [0.05, 2.16]
  1 study · 43 participants
  Very low

AB103 vs placebo

It is very uncertain whether AB103 changes serious adverse events (SAE) compared with placebo (very low certainty).

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  RR 1.49 [0.52, 4.27]
  1 study · 43 participants
  Very low

AB103 vs placebo

The review found no eligible studies for this question.

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

AB103 vs placebo

The review found no eligible studies for this question.

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

IVIg vs placebo

Intravenous immunoglobulin showed no clear difference in mortality compared with placebo (low certainty).

• Interventions for necrotizing soft tissue infections in adults 2018 · Cochrane Headline outcomes only
  RR 1.17 [0.42, 3.23]
  1 study · 100 participants
  Low

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 260 participants
  Very low

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 80 participants
  Very low

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 283 participants
  Very low

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 283 participants
  Very low

Nivolumab vs no other intervention

The review found no eligible studies for this question.

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 283 participants
  Very low

Nivolumab vs no other intervention

• Nivolumab for adults with Hodgkin's lymphoma (a rapid review using the software RobotReviewer) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 243 participants
  Very low

Erbium:YAG laser vs Flap elevation at implant exposure

Erbium:YAG laser (implant exposure) led to lower postoperative pain compared with flap elevation at implant exposure; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  RR 0.25 [0.07, 0.90]
  1 study · 20 participants
  GRADE not reported

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Subepithelial connective tissue graft (palate) at implant placement showed no clear difference in peri-implant marginal bone level change compared with no augmentation; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  MD 0.17 [-0.10, 0.44]
  1 study · 20 participants
  GRADE not reported

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Subepithelial connective tissue graft (palate) at implant placement led to lower patient preference (aesthetics evaluated by patients) compared with no augmentation; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  OR 0 [0, 0.85]
  1 study · 10 participants
  GRADE not reported

Flapless implant placement vs Conventional flap elevation

Flapless implant placement showed no clear difference in biological complications compared with conventional flap elevation; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  RR 5.58 [0.65, 48.23]
  1 study · 80 participants
  GRADE not reported

Flapless implant placement vs Conventional flap elevation

Flapless implant placement led to lower postoperative pain compared with conventional flap elevation; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  MD -1.1 [-2.02, -0.18]
  1 study · 80 participants
  GRADE not reported

Flapless implant placement vs Conventional flap elevation

Flapless implant placement showed no clear difference in peri-implant marginal bone level change compared with conventional flap elevation; GRADE not reported.

• Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
  MD -0.05 [-0.25, 0.15]
  1 study · 78 participants
  GRADE not reported