Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

188 questions · 190 findings · 13 reviews · Headline outcomes only

No studies found 50 · 26.3%GRADE not reported 0 · 0%Very low 48 · 25.3%Low 52 · 27.4%Moderate 30 · 15.8%High 10 · 5.3%

Aspirin plus antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Global state: any change in global state – unspecified problem necessitating change in dose or type of antipsychotics – medium term · patients with schizophrenia

It is very uncertain whether aspirin plus antipsychotics changes global state: any change in global state – unspecified problem… compared with placebo plus antipsychotics (very low certainty).

1 finding from 1 review

Aspirin plus antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

It is very uncertain whether aspirin plus antipsychotics changes leaving the study early: short‐term – for any reason compared with placebo plus antipsychotics (very low certainty).

1 finding from 1 review

Aspirin plus antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Adverse events: gastrointestinal – dyspeptic symptoms – self‐assessed as at least 'moderate' · patients with schizophrenia

It is very uncertain whether aspirin plus antipsychotics changes adverse events: gastrointestinal – dyspeptic symptoms –… compared with placebo plus antipsychotics (very low certainty).

1 finding from 1 review