Findings

What do systematic reviews say?

171 questions · 174 findings · 15 reviews

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No studies found 48 · 27.6%GRADE not reported 13 · 7.5%Very low 61 · 35.1%Low 33 · 19%Moderate 15 · 8.6%High 4 · 2.3%

Intervention not reported

True positivespeople with amikacin resistance · adults with pulmonary tuberculosis with known rifampicin resistance, detected as tuberculosis‐positive by Xpert MTB/XDR Index test: Xpert…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 65 participants
Low

Intervention not reported

False negativespeople incorrectly classified as not having amikacin resistance · adults with pulmonary tuberculosis with known rifampicin resistance, detected as tuberculosis‐positive by Xpert MTB/XDR Index test: Xpert…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 65 participants
Low

Intervention not reported

True negativespeople without amikacin resistance · adults with pulmonary tuberculosis with known rifampicin resistance, detected as tuberculosis‐positive by Xpert MTB/XDR Index test: Xpert…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 425 participants
High

Intervention not reported

False positivespeople incorrectly classified as having amikacin resistance · adults with pulmonary tuberculosis with known rifampicin resistance, detected as tuberculosis‐positive by Xpert MTB/XDR Index test: Xpert…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 425 participants
High

Intervention not reported

False negativespeople incorrectly classified as not having pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 799 participants
Very low

Intervention not reported

True negativespeople without pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 429 participants
Very low

Intervention not reported

False positivespeople incorrectly classified as having pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 429 participants
Very low

Intervention not reported

Test result · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

True positivespeople with isoniazid resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 756 participants
Moderate

Intervention not reported

False negativespeople incorrectly classified as not having isoniazid resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 756 participants
Moderate

Intervention not reported

True negativespeople without isoniazid resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 327 participants
Moderate