Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

625 questions · 647 findings · 67 reviews · Pregnancy and Childbirth

No studies found 83 · 12.8%GRADE not reported 70 · 10.8%Very low 141 · 21.8%Low 227 · 35.1%Moderate 97 · 15%High 29 · 4.5%

Paracetamol vs placebo

Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes maternal adverse events (up to 4 hours and at 6 hours) compared with placebo (very low certainty).

1 finding from 1 review

NSAIDs vs placebo

Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.

NSAID showed no clear difference in maternal adverse events (4 to 8 hours) compared with placebo (low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs placebo (water pack)

Perineal oedema within 4 ‐ 6 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

Cooling treatment (ice pack) showed no clear difference in perineal oedema within 4 ‐ 6 hours after giving birth compared with placebo (water pack) (low certainty).

1 finding from 1 review

Cooling treatment (ice pack) vs placebo (water pack)

Perineal oedema within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth

Cooling treatment (ice pack) showed no clear difference in perineal oedema within 24 hours after giving birth compared with placebo (water pack) (low certainty).

1 finding from 1 review