Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

351 questions · 362 findings · 10 reviews · Oral Health

No studies found 41 · 11.3%GRADE not reported 285 · 78.7%Very low 10 · 2.8%Low 18 · 5%Moderate 8 · 2.2%High 0 · 0%

Chlorhexidine vs Cryotherapy (ice chips) 60 minutes

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Chlorhexidine showed no clear difference in oral mucositis (moderate to severe) compared with cryotherapy (ice chips); GRADE not reported.

1 finding from 1 review

Low‐level laser therapy vs Placebo or no active treatment

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Laser (low level) showed no clear difference in oral mucositis (moderate to severe) compared with placebo/sham/no treatment; GRADE not reported.

1 finding from 1 review

Cryotherapy (ice chips) 30 minutes vs Cryotherapy (ice chips) 60 minutes

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Cryotherapy (ice chips) 30 minutes showed no clear difference in oral mucositis (moderate to severe) compared with cryotherapy (ice chips) 60 minutes; GRADE not reported.

1 finding from 1 review

Yangyin-humo decoction vs Traditional Western medicine

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Yangyin-humo decoction showed no clear difference in oral mucositis (moderate to severe) compared with traditional Western medicine; GRADE not reported.

1 finding from 1 review