Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

341 questions · 354 findings · 26 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 58 · 16.4%GRADE not reported 4 · 1.1%Very low 51 · 14.4%Low 133 · 37.6%Moderate 82 · 23.2%High 26 · 7.3%

Probiotics vs other active intervention

Grade ≥ 3 diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)

Probiotics may leads to lower severity of diarrhoea: grade 3 or higher compared with other active treatment (low certainty).

1 finding from 1 review

Probiotics vs other active intervention

Requiring rescue medication for diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)

It is very uncertain whether probiotics changes requiring rescue medication for diarrhoea compared with other active treatment (very low certainty).

1 finding from 1 review

Probiotics vs placebo

Median (mean) time to use of rescue medication · participants with cancer treated with radiotherapy (with or without chemotherapy)
2 findings from 1 review