Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

178 questions · 181 findings · 13 reviews

No studies found 33 · 18.2%GRADE not reported 13 · 7.2%Very low 46 · 25.4%Low 37 · 20.4%Moderate 42 · 23.2%High 10 · 5.5%

ZOTEPINE vs REMOXIPRIDE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

ZOTEPINE showed no clear difference in adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with REMOXIPRIDE (low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Global state: No clinically important response (as defined by the original studies) · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes global state: No clinically important response (as defined by the… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 4mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 8mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review