Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

285 questions · 290 findings · 75 reviews · Headline outcomes only

No studies found 81 · 27.9%GRADE not reported 18 · 6.2%Very low 91 · 31.4%Low 62 · 21.4%Moderate 32 · 11%High 6 · 2.1%

Isopropyl alcohol vs usual care

Rescue antiemetic · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

Isopropyl alcohol probably leads to lower use of rescue antiemetics Assessed by proportion requiring antiemetics compared with standard treatment (moderate certainty).

1 finding from 1 review

Isopropyl alcohol vs Normal saline

Rescue antiemetic · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

It is very uncertain whether isopropyl alcohol changes use of rescue antiemetics Assessed by proportion requiring rescue… compared with saline (very low certainty).

1 finding from 1 review

Aromatherapy vs placebo

Rescue antiemetic · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

Aromatherapy may leads to lower proportion requiring rescue antiemetics Assessed by numbers of… compared with placebo (low certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs ATYPICAL DEPOT ANTIPSYCHOTICS (PALIPERIDONE PALMITATE)

Adverse events: Any prolactin‐related ‐ medium term · patients with schizophrenia

RISPERIDONE DEPOT showed no clear difference in adverse events: Any prolactin‐related ‐ medium term compared with ATYPICAL DEPOT ANTIPSYCHOTICS (PALIPERIDONE PALMITATE) (moderate certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs ATYPICAL DEPOT ANTIPSYCHOTICS (PALIPERIDONE PALMITATE)

Adverse events: Any glucose‐related ‐ medium/long term · patients with schizophrenia

RISPERIDONE DEPOT showed no clear difference in adverse events: Any glucose‐related ‐ medium/long term compared with ATYPICAL DEPOT ANTIPSYCHOTICS (PALIPERIDONE PALMITATE) (low certainty).

1 finding from 1 review