What do systematic reviews say?

Calcitriol vs ergocalciferol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Calcitriol vs ergocalciferol

It is very uncertain whether calcitriol changes hypercalcaemia compared with ergocalciferol (very low certainty).

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  RR 1.75 [0.68, 4.5]
  1 study · 15 participants
  Very low

Calcitriol vs ergocalciferol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Calcitriol vs ergocalciferol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Calcitriol vs ergocalciferol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Calcium carbonate vs aluminium hydroxide

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Very low

Calcium carbonate vs aluminium hydroxide

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Very low

Calcium carbonate vs aluminium hydroxide

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Very low

Calcium carbonate vs aluminium hydroxide

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Very low

Summary of findings: Sevelamer vs calcium carbonate

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

Summary of findings: Sevelamer vs calcium carbonate

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

Summary of findings: Sevelamer vs calcium carbonate

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

Summary of findings: Sevelamer vs calcium carbonate

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

Summary of findings: Sevelamer vs calcium carbonate

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

Intermittent oral vs oral calcitriol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 24 participants
  Very low

Vertical distraction osteogenesis vs Autogenous onlay bone graft (mandibular ramus)

Vertical distraction osteogenesis showed no clear difference in augmentation procedure (partial) failure compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.

• Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes

  Up to 3 years post-loading
  OR 0.88 [0.05, 16.74]
  1 study · 17 participants
  GRADE not reported

Vertical distraction osteogenesis vs Autogenous inlay bone graft (iliac crest)

Vertical distraction osteogenesis showed no clear difference in complications compared with autogenous inlay bone graft (iliac crest); GRADE not reported.

• Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes

  At least 1.5 years post-loading
  OR 7.50 [0.46, 122.70]
  1 study · 11 participants
  GRADE not reported

Vertical distraction osteogenesis vs Autogenous onlay bone graft (mandibular ramus)

Vertical distraction osteogenesis showed no clear difference in complication at augmented + donor site compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.

• Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes

  Up to 3 years post-loading
  OR 0.5 [0.07, 3.55]
  1 study · 17 participants
  GRADE not reported

Vertical distraction osteogenesis vs Vertical GBR with non-resorbable barriers + particulate autogenous bone

Vertical distraction osteogenesis showed no clear difference in complication at augmentation + donor site compared with vertical GBR with non-resorbable barriers + particulate autogenous…; GRADE not reported.

• Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes

  Up to 3 years post-loading
  OR 0.3 [0.04, 2.11]
  1 study · 21 participants
  GRADE not reported

Intervention not reported

The intervention may leads to lower pegylated interferon beta‐1a (Direct evidence; 1 RCT; 1512… (low certainty).

• Immunomodulators and immunosuppressants for relapsing‐remitting multiple sclerosis: a network meta‐analysis 2024 · Cochrane Headline outcomes only
  RR 0.68 [0.56, 0.82]
  1 study · 1512 participants
  Low