Proportion developing new caries · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1450 ppm F toothpaste probably leads to lower proportion developing new caries compared with 440 ppm F toothpaste (moderate certainty).
1 finding from 1 review
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
1 finding from 1 review
Completion of dental treatment · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
It is very uncertain whether acupressure at P6 point with device plus sedation changes completion of dental procedure compared with sham (dummy) acupressure with sedation (very low certainty).
1 finding from 1 review
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Caries increment, surface index D(M)FS · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1500 ppm F toothpaste probably leads to lower caries increment, surface index d(m)fs compared with non-fluoride (0 ppm F) placebo toothpaste (moderate certainty).
1 finding from 1 review
Restoration failure · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
2 findings from 1 review
Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
Interventions for managing halitosis 2019 · Cochrane All outcomesmean 8 days
Adverse events (Table 12). Risk with Perio-plus mouthrinse: 1 patient reported unpleasant feeling after the use of the product; there were no severe adverse events reported. Risk with halita mouthrinse: 1 patient…
1 study · 36 participants
Very low
Change in haemoglobin level from baseline · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
1 finding from 1 review
Mean fall in haemoglobin. Forbes (TXA): 1.4 g/100 mL (placebo) vs 0.3 g/100 mL (TXA). Walsh (EACA): 6.3% (placebo, both centres) vs 3.9% and 3.7% (EACA, centres 1 and 2); differences not significant. Reported in…
2 studies · 59 participants
GRADE not reported
Completion of dental treatment · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled children
The review found no eligible studies for this question.
1 finding from 1 review
Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste may leads to lower caries increment, surface index D(M)FS compared with 250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.26 [-0.38, -0.14]
Studies not reported
Low
Volatile sulphur compounds (VSC), gas chromatography · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
Number of adverse events · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis
The review found no eligible studies for this question.
1 finding from 1 review
Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Professionally-applied fluoride varnish (7700 or 10,000 ppm F),… showed no clear difference in number of participants with new demineralised lesions (DLs) compared with non-fluoride (placebo) varnish (low certainty).
1 finding from 1 review
Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
Patil 2017 reported burning mucosa and drying of mouth in a few subjects using the control drug (chlorhexidine) and no adverse effects were reported in the intervention group (G32 tablets).
1 study · 40 participants
GRADE not reported
Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
1 finding from 1 review
Adverse effects: 33 participants (1 RCT, Zotelli 2014); very low certainty. The trial authors were unsure whether the reported adverse events (one control participant reported increased sweating) were due to…
1 study · 33 participants
Very low
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Miswak (Salvadora persica) mouthwash showed no clear difference in volatile sulphur compounds (VSC) compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Number of participants with more severe DLs (score 3 or 4 versus 1 or 2) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Professionally-applied fluoride varnish (7700 ppm F ammonium… may leads to lower number of participants with more severe DLs (score 3 or 4 versus 1… compared with non-fluoride (placebo) varnish (low certainty).
1 finding from 1 review
Plaque · People with mixed levels of ID (age range unclear); setting residential
Oral hygiene care training of carers showed no clear difference in plaque (medium term) compared with no training (or a placebo training session) of carers (low certainty).
1 finding from 1 review