Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,327 questions · 2,494 findings · 87 reviews · All outcomes

No studies found 450 · 18%GRADE not reported 1,487 · 59.6%Very low 385 · 15.4%Low 121 · 4.9%Moderate 50 · 2%High 1 · 0%

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate showed no clear difference in complications (adverse effects) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Marginal bone level change · Partially edentulous patients receiving posterior mandibular implants

Subepithelial connective tissue graft (palate) at implant placement showed no clear difference in peri-implant marginal bone level change compared with no augmentation; GRADE not reported.

1 finding from 1 review

Ceramic implant abutment vs Metal implant abutments (titanium)

Overall success rate · Patients receiving implant-supported single crowns / short-span FDPs
1 finding from 1 review
  • Andersson 2003: 94% (16/17) ceramic vs 100% (12/12) titanium; Andersson 2001: 93% (28/30) ceramic vs 100% (35/35) titanium; no statistical analysis provided; no measurable / non-significant differences in alveolar bone…
    2 studies · 107 participants
    GRADE not reported

Alternative alloy FDP (e.g., Ceramalloy II / base-metal / palladium-silver) vs High-gold content control alloy FDP (Olympia)

Restoration survival · Patients receiving crowns and FDPs; split-mouth, 10-year

Alternative alloy FDP (e.g., Ceramalloy II / base-metal /… led to higher restoration survival (Ceramalloy II versus Olympia) compared with high-gold content control alloy FDP (Olympia); GRADE not reported.

1 finding from 1 review

Topical ciclosporin 1.5% gel vs Topical clobetasol propionate 0.025% gel

Physician Global Assessment (Thongprasom score) · People with erosive oral lichen planus

Topical ciclosporin 1.5% gel showed no clear difference in physician Global Assessment (Thongprasom score) compared with topical clobetasol propionate 0.025% gel; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in gingival recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in gingival recession (REC) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Denzir all-ceramic FDP vs In-Ceram Zirconia all-ceramic FDP

Reconstruction failure / chip fractures (12 months) · Patients with all-ceramic implant FDP reconstructions; parallel group, 12-month
1 finding from 1 review

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Aesthetic preference evaluated by the patient (split-mouth design studies) · Partially edentulous patients receiving posterior mandibular implants

Subepithelial connective tissue graft (palate) at implant placement led to lower patient preference (aesthetics evaluated by patients) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in probing attachment level (PAL) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Any topical or systemic intervention vs Placebo, no treatment, or another intervention

Outcome not reported · People with erosive anogenital (genital) lichen planus

The review found no eligible studies for this question.

1 finding from 1 review