Findings

What do systematic reviews say?

2,261 questions · 2,280 findings · 114 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 856 · 37.5%GRADE not reported 58 · 2.5%Very low 550 · 24.1%Low 502 · 22%Moderate 271 · 11.9%High 43 · 1.9%

Summary of findings: water‐soluble vitamin E vs control

Retinopathy due to vitamin E deficiency · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: water‐soluble vitamin E vs control

Body‐mass index (BMI) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: water‐soluble vitamin E vs control

Height (cm) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: water‐soluble vitamin E vs control

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: fat‐soluble vitamin E vs control

Vitamin E total lipid ratio · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: fat‐soluble vitamin E vs control

Vitamin E levels in serum: umol/L · adults and children with cystic fibrosis

1 finding from 1 review

Vitamin E supplementation in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
6 participants
GRADE not reported

Intervention not reported

FEV1 change from start of treatment (L) · adults and children with cystic fibrosis and P aeruginosa

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 68 participants
High

Intervention not reported

FEV1 change from start of treatment (% predicted) · adults and children with cystic fibrosis and P aeruginosa

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Moderate

Intervention not reported

Time to next exacerbation · adults and children with cystic fibrosis and P aeruginosa

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Moderate

Intervention not reported

Adverse events: number of moderate adverse events · adults and children with cystic fibrosis and P aeruginosa

The intervention showed no clear difference in adverse events: number of moderate adverse events (moderate certainty).

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
RR 0.36 [0.07, 1.77]
2 studies · 73 participants
Moderate

Intervention not reported

Sputum density: change in P aeruginosa sputum density (log1₀ CFU/g) · adults and children with cystic fibrosis and P aeruginosa

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 70 participants
High

Intervention not reported

Quality of life: change in CFQ‐R score from start of treatment · adults and children with cystic fibrosis and P aeruginosa

1 finding from 1 review

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Moderate

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Mood or personal well‐being · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ computerised learning vs no intervention

QoL · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Summary of findings ‐ computerised learning vs no intervention

Compliance or adherence to the trial intervention (including satisfaction for it) · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Summary of findings ‐ computerised learning vs no intervention

Physical health · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ computerised learning vs no intervention

Cost of psychological intervention · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ computerised learning vs no intervention

Family adjustment · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ auto‐hypnosis (self‐hypnosis) vs control

Mood or personal well‐being: change in distress (according to General Severity Index) · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Summary of findings ‐ auto‐hypnosis (self‐hypnosis) vs control

Coping strategies · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found